Detail Information of hs0000099 [Genome Browser]
1.Basic Information

Name: hs0000099
Species: Homo sapiens
Cell Line: fetal liver
Restriction Enzyme: EcoRI

2.Experiment Infromation

Remark: control: brain cells; ln2-Ik(null) fetal liver cells(Homozygous line 2) display higher amplification frequencies between HS2-4/γ(G)γ(A) genes, HS2-4/γ(A) genes
Primer amount: NA
Test repetition: at least t
Reliability Level: I

3.Locus Information

Anchor
Locus1 Fragment location Primer sequence Strand
HBB,LCR HS2 to HS4 11:5300235-5310660 ATAGCTTGTCTATTTCTCTCTCTAACATAGTTG -
Target
Locus2 Fragment location Primer sequence Strand
HBG1 11:5269664-5272311 TTCTCTGAAAGTGATCCATGATCTCT +

4.Reference

Bottardi, S., et al. (2009). "Ikaros and GATA-1 combinatorial effect is required for silencing of human gamma-globin genes." Mol Cell Biol 29(6): 1526-1537.   PMID: 19114560

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