Name:
hs0000640
Species:
Homo sapiens
Cell Line:
U937
Restriction Enzyme:
NspI
Remark:
RA treatment chromatin change;in the presence of retinoic acid(RA), GA-binding protein(GABP) and p300 at the proximal promoter recruit retinoic acid receptor/retinoid X receptor from a distal RARE to form an enhanceosome
Primer amount:
NA
Test repetition:
NA
Reliability Level:
I
| Anchor | |||
|---|---|---|---|
| Locus1 | Fragment location | Primer sequence | Strand |
ITGB2,enhanceosome,proximal promoter |
21:46340319-46340986 | TAGAAACCTCAGCTGGAGGC | + |
| Target | |||
| Locus2 | Fragment location | Primer sequence | Strand |
|
ITGB2,distal enhancer |
21:46341782-46342263 | GAAGGCAGAGGTGGATGGA | - |
Resendes, K. K. and A. G. Rosmarin (2006). "GA-binding protein and p300 are essential components of a retinoic acid-induced enhanceosome in myeloid cells." Mol Cell Biol 26(8): 3060-3070. PMID: 16581781
| ©BIG 2015, Beijing Institute of Genomics, Chinese Academy of Sciences
NO.1 Beichen West Road, Chaoyang District, Beijing 100101, China.
|