Detail Information of hs0000258 [Genome Browser]
1.Basic Information

Name: hs0000258
Species: Homo sapiens
Cell Line: SU-DHL-4
Restriction Enzyme: BamHI

2.Experiment Infromation

Remark: compare site 10;not in DHL-9 cells(DHL-4 cells have the t(14;18) translocation, and DHL-9 cells lack this translocation.); frequency of site1,2 higher than site3;specially in site 6,8(HS4);TSA treatment decrease frequency of site1,2;
Primer amount: NA
Test repetition: three
Reliability Level: II

3.Locus Information

Anchor
Locus1 Fragment location Primer sequence Strand
BCL2,promoter,segment 1 18:60989802-60993758 CAAGATGCCACATAAGGAATCAGTC/CCTTTGCTCCCACAGAGCCTCACTCTATG -
Target
Locus2 Fragment location Primer sequence Strand
IgH,3' enhancer,downstream of Cα1 and Cα2 site 8 14:106151813-106159008 TCCAGGGAGGACTCAAGTTTGAG -

4.Reference

Duan, H., et al. (2008). "Functional long-range interactions of the IgH 3' enhancers with the bcl-2 promoter region in t(14;18) lymphoma cells." Oncogene 27(53): 6720-6728.   PMID: 18695675

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